Article
IGF(CA)19 and IGFBP-3-202A/C gene polymorphism in patients with acromegaly.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 1 Dec 2010
Akin Fulya, Turgut Sebahat, Cirak Bayram, Kursunluoglu Raziye
Abstract excerpt
OBJECTIVE: We aimed to investigate IGF-1 and IGFBP-3 gene polymorphisms in patients with acromegaly. DESIGN: We included 34 patients with acromegaly and 37 healthy subjects to study. At baseline examinations, antropometric measurements were done. Genomic DNA from the patients and controls were prepared. Serum, glucose, insulin, total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol, growth hormone...
Topics
- Acromegaly
- Adult
- Aged
- Case-Control Studies
- Dinucleotide Repeats
- Drug Resistance
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Insulin-Like Growth Factor Binding Protein 3
- Insulin-Like Growth Factor I
- Male
- Middle Aged
- Polymorphism, Genetic
- Polymorphism, Single Nucleotide
- Promoter Regions, Genetic