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Article

Mutation scanning in a single and a stacked genetically modified (GM) event by real-time PCR and high resolution melting (HRM) analysis.

International journal of molecular sciences - 31 Oct 2014

Ben Ali Sina-Elisabeth, Madi Zita Erika, Hochegger Rupert, Quist David, Prewein Bernhard, Haslberger Alexander G, Brandes Christian

Abstract excerpt

Genetic mutations must be avoided during the production and use of seeds. In the European Union (EU), Directive 2001/18/EC requires any DNA construct introduced via transformation to be stable. Establishing genetic stability is critical for the approval of genetically modified organisms (GMOs). In this study, genetic stability of two GMOs was examined using high resolution melting (HRM) analysis and real-time...

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Identifiers

PMID: 25365178
DOI: 10.3390/ijms151119898
PMCID: PMC4264145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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