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Article

Elevation of peripheral BDNF promoter methylation links to the risk of Alzheimer's disease.

PloS one - 1 Jan 2014

Chang Lan, Wang Yunliang, Ji Huihui, Dai Dongjun, Xu Xuting, Jiang Danjie, Hong Qingxiao, Ye Huadan, Zhang Xiaonan, Zhou Xiaohui, Liu Yu, Li Jinfeng, Chen Zhongming, Li Ying, Zhou Dongsheng, Zhuo Renjie, Zhang Yuzheng, Yin Honglei, Mao Congcong, Duan Shiwei, Wang Qinwen

Abstract excerpt

Brain derived neurotrophic factor (BDNF) has been known to play an important role in various mental disorders or diseases such as Alzheimer's disease (AD). The aim of our study was to assess whether BDNF promoter methylation in peripheral blood was able to predict the risk of AD. A total of 44 AD patients and 62 age- and gender-matched controls were recruited in the current case-control study. Using the...

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Identifiers

PMID: 25364831
DOI: 10.1371/journal.pone.0110773
PMCID: PMC4217733

Genes

BDNF
CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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