Article
Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer’s disease
2 Sept 2019
Abstract excerpt
BACKGROUND: Alzheimer's disease results from a neurodegenerative process that starts well before the diagnosis can be made. New prognostic or diagnostic markers enabling early intervention into the disease process would be highly valuable. Environmental and lifestyle factors largely modulate the disease risk and may influence the pathogenesis through epigenetic mechanisms, such as DNA methylation. As...
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