Riluzole is a radio‐sensitizing agent in an in vivo model of brain metastasis derived from <scp>GRM</scp>1 expressing human melanoma cells

Abstract excerpt

Approximately 50% of patients having metastatic melanoma develop brain metastases during the course of their illness. Evidence exists that melanoma cells have increased aptitude for the repair of sublethal DNA damage caused by ionizing radiation therapy. To address the radio-resistance of melanoma, many groups adopted radiotherapy schedules that deliver larger daily fractions of radiation, but due to the risk of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to bioluminescence and chemiluminescence research
• Share to Brain Metastases and Treatment