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Article

Association of variation in the LAMA3 gene, encoding the alpha-chain of laminin 5, with atopic dermatitis in a German case-control cohort.

BMC dermatology - 3 Nov 2014

Stemmler Susanne, Parwez Qumar, Petrasch-Parwez Elisabeth, Epplen Joerg T, Hoffjan Sabine

Abstract excerpt

BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disorder caused by complex interaction of genetic and environmental factors. Besides mutations in the filaggrin gene, leading to impaired skin barrier function, variation in genes encoding additional skin proteins has been suggested to contribute to disease risk. Laminin 5, playing an important role in skin integrity, is composed of three subunits...

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Source

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Identifiers

PMID: 25363238
DOI: 10.1186/1471-5945-14-17
PMCID: PMC4221780

Genes

LAMA3
LAMB3
LAMC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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