Article
Scanning indels in the 5q22.1 region and identification of the TMEM232 susceptibility gene that is associated with atopic dermatitis in the Chinese Han population.
Gene - 20 Jun 2017
Wu Yan-Yan, Tang Jian-Ping, Liu Qiang, Zheng Xiao-Dong, Fang Ling, Yin Xian-Yong, Jiang Xiao-Yun, Zhou Fu-Sheng, Zhu Fei, Liang Bo, Li Yang, Zuo Xian-Bo, Zhang Xue-Jun, Xiao Feng-Li
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease. The 5q22.1 region was found to have an association with AD in our previous genome-wide association study (GWAS). OBJECTIVE: To identify the AD susceptibility gene in 5q22.1 and observe its expression in AD tissues. METHODS: Suggestive indels from the GWAS data were genotyped in 3013 AD patients and 5075 controls from the Chinese Han...
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