A stop-gain in the laminin, alpha 3 gene causes recessive junctional epidermolysis bullosa in Belgian Blue cattle.

doi:10.1111/age.12342

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

A stop-gain in the laminin, alpha 3 gene causes recessive junctional epidermolysis bullosa in Belgian Blue cattle.

Animal genetics - 1 Oct 2015

Sartelet Arnaud, Harland Chad, Tamma Nico, Karim Latifa, Bayrou Calixte, Li Wanbo, Ahariz Naima, Coppieters Wouter, Georges Michel, Charlier Carole

Abstract excerpt

Four newborn purebred Belgian Blue calves presenting a severe form of epidermolysis bullosa were recently referred to our heredo-surveillance platform. SNP array genotyping followed by autozygosity mapping located the causative gene in a 8.3-Mb interval on bovine chromosome 24. Combining information from (i) whole-genome sequencing of an affected calf, (ii) transcriptomic data from a panel of tissues and (iii) a...

Topics

Animals
Cattle
Cattle Diseases
Chromosome Mapping
DNA Mutational Analysis
Epidermolysis Bullosa, Junctional
Ethanolaminephosphotransferase
Genotype
Laminin
Transcriptome

Source

Open in PubMed

Identifiers

PMID: 26370913
DOI: 10.1111/age.12342

Genes

LAMA3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics