Article
Evaluation of KRAS Gene Expression and LCS6 Variant in Genomic and Cell-Free DNA of Iranian Women With Endometriosis.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Jun 2015
Farahani Maryam Shahrabi, Shahbazi Shirin, Moghaddam Soheila Amini, Mahdian Reza
Abstract excerpt
Since the activation of KRAS results in de novo endometriosis in mice, KRAS is regarded as a crucial gene in ectopic endometrial implantation. Recently, it has been reported that 31% of women with endometriosis have KRAS let-7 complementary binding site 6 single-nucleotide polymorphism (LCS6 SNP). This study addresses the correlation between KRAS LCS6 SNP and endometriosis in a case-control study. To detect...
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