Article
No evidence for genetic association with the let-7 microRNA-binding site or other common KRAS variants in risk of endometriosis.
Human reproduction (Oxford, England) - 1 Dec 2012
Luong Hien T T, Nyholt Dale R, Painter Jodie N, Chapman Brett, Kennedy Stephen, Treloar Susan A, Zondervan Krina T, Montgomery Grant W
Abstract excerpt
STUDY QUESTION: Is there a contribution of the minor allele at the KRAS single nucleotide polymorphism (SNP) rs61764370 in the let-7 microRNA-binding site to endometriosis risk? SUMMARY ANSWER: We found no evidence for association between endometriosis risk and rs61764370 or any other SNPs in KRAS. WHAT IS KNOWN ALREADY: The rs61764370 SNP in the 3' untranslated region of the KRAS gene is predicted to disrupt a...
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