Article
KRAS mutations and endometriosis burden of disease.
The journal of pathology. Clinical research - 1 Jul 2023
Orr Natasha L, Albert Arianne, Liu Yang Doris, Lum Amy, Hong JooYoon, Ionescu Catalina L, Senz Janine, Nazeran Tayyebeh M, Lee Anna F, Noga Heather, Lawrenson Kate, Allaire Catherine, Williams Christina, Bedaiwy Mohamed A, Anglesio Michael S, Yong Paul J
Abstract excerpt
The clinical phenotype of somatic mutations in endometriosis is unknown. The objective was to determine whether somatic KRAS mutations were associated with greater disease burden in endometriosis (i.e. more severe subtypes and higher stage). This prospective longitudinal cohort study included 122 subjects undergoing endometriosis surgery at a tertiary referral center between 2013 and 2017, with 5-9 years of...
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