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Article

Conditionally induced RAGE expression by proximal airway epithelial cells in transgenic mice causes lung inflammation.

Respiratory research - 29 Oct 2014

Bodine B Garrett, Bennion Brock G, Leatham Emma, Jimenez Felix R, Wright Alex J, Jergensen Zac R, Erickson Connor J, Jones Cameron M, Johnson Jeff P, Knapp Steven M, Reynolds Paul R

Abstract excerpt

BACKGROUND: Receptors for advanced glycation end-products (RAGE) are multiligand cell-surface receptors expressed abundantly by distal pulmonary epithelium. Our lab has discovered RAGE-mediated effects in the orchestration of lung inflammation induced by tobacco smoke and environmental pollutants; however, the specific contribution of RAGE to the progression of proximal airway inflammation is still inadequately...

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Identifiers

PMID: 25359169
DOI: 10.1186/s12931-014-0133-y
PMCID: PMC4219035

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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