Article
Induction of macrophage-like immunosuppressive cells from mouse ES cells that contribute to prolong allogeneic graft survival.
PloS one - 1 Jan 2014
Kudo Hiroya, Wada Haruka, Sasaki Hajime, Tsuji Hyuma, Otsuka Ryo, Baghdadi Muhammad, Kojo Satoshi, Chikaraishi Tatsuya, Seino Ken-ichiro
Abstract excerpt
Recent progress in regenerative medicine has enabled the utilization of pluripotent stem cells (PSCs) such as embryonic stem cells (ESCs) as a donor resource for transplantation. However, immune suppression is still needed when the donor-recipient combination is allogeneic. Protection of ESCs-derived grafts from host immune response might be achieved thought the utilization of immunosuppressive cells generated...
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