Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mesenchymal stem cells might be used to induce tolerance in heart transplantation.

Medical hypotheses - 1 Jan 2008

Zhou Heping, Jin Zhenxiao, Liu Jincheng, Yu Shiqiang, Cui Qin, Yi Dinghua

Abstract excerpt

Heart transplantation is the last treatment selection for end-stage heart diseases, but the side-effects of immunosuppressive agents and morbidity brought by lifelong immunosuppression still remains unavoidable. Mesenchymal stem cell (MSC) is one kind of adult pluripotent cell that not only can differentiate into cardiomyocytes but also maintain some unique immunomodulatory function. There were reports that MSCs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Transplantation
Share to Constriction, Pathologic
Share to Heart Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immune System

Share to Immunosuppressive Agents

Share to Mesenchymal Stem Cells

Share to Transplantation, Homologous

Share to Transplantation Tolerance

Source

Identifiers

PMID: 17959317
DOI: 10.1016/j.mehy.2007.08.010

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mesenchymal stem cells might be used to induce tolerance in heart transplantation.PMID 17959317Read ↗

Concise Review: Immunomodulatory Properties of Mesenchymal Stem Cells in Cellular Transplantation: Update, Controversies, and UnknownsSemantic proximity Read ↗

Clinical translation of mesenchymal stem cells in ischemic heart failure: Challenges and future perspectivesSemantic proximity Read ↗

iPSC modification strategies to induce immune toleranceSemantic proximity Read ↗

Netrin-1 prolongs skin graft survival by inducing the transformation of mesenchymal stem cells from pro-rejection to immune-tolerant phenotype.Semantic proximity Read ↗

hESC-derived immune suppressive dendritic cells induce immune tolerance of parental hESC-derived allograftsSemantic proximity Read ↗

Immune reaction and regulation in transplantation based on pluripotent stem cell technologySemantic proximity Read ↗

Regulatory T Cells in Chronic Heart Failure.Semantic proximity Read ↗

Induction of macrophage-like immunosuppressive cells from mouse ES cells that contribute to prolong allogeneic graft survival.Semantic proximity Read ↗

HLA‐E high /HLA‐G high /HLA‐II low Human iPSC‐Derived Cardiomyocytes Exhibit Low Immunogenicity for Heart RegenerationSemantic proximity Read ↗

Approaches for immunological tolerance induction to stem cell-derived cell replacement therapiesSemantic proximity Read ↗

Heart grafts tolerized through third-party multipotent adult progenitor cells can be retransplanted to secondary hosts with no immunosuppression.Semantic proximity Read ↗

Immunological properties of embryonic and adult stem cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.