Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Embryonic Stem Cells: Overcoming the Immunological Barriers to Cell Replacement Therapy

1 Jan 2009

Abstract excerpt

The appeal of using embryonic stem (ES) cells for regenerative medicine lies in their pluripotency and resulting ability to differentiate into all somatic cell types. While graft rejection remains the greatest hurdle to their use in the clinic, several approaches have been proposed to protect the allogeneic ES cell-derived grafts from host immunity: the creation of nuclear transfer human ES (hES) cell lines; the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to CRISPR and Genetic Engineering
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19149632
DOI: 10.2174/157488809787169093

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Embryonic Stem Cells: Overcoming the Immunological Barriers to Cell Replacement TherapyPMID 19149632Read ↗

iPSC modification strategies to induce immune toleranceSemantic proximity Read ↗

Approaches for immunological tolerance induction to stem cell-derived cell replacement therapiesSemantic proximity Read ↗

Immunogenicity of embryonic stem cell-derived progenitors after transplantationSemantic proximity Read ↗

Transplanting stem cells: Potential targets for immune attack. Modulating the immune response against embryonic stem cell transplantationSemantic proximity Read ↗

Concise Review: Immune Recognition of Induced Pluripotent Stem CellsSemantic proximity Read ↗

human embryonic stem cells: biology and clinical implicationsSemantic proximity Read ↗

Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-toleranceSemantic proximity Read ↗

Pluripotent Stem Cells: Immune to the Immune System?Semantic proximity Read ↗

Concise Review: One Stone for Multiple Birds: Generating Universally Compatible Human Embryonic Stem CellsSemantic proximity Read ↗

Human Embryonic Stem Cells Possess Immune‐Privileged PropertiesSemantic proximity Read ↗

Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of toleranceSemantic proximity Read ↗

Clinical tolerance in allogeneic hematopoietic stem cell transplantationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.