Article
Induction of macrophage-like immunosuppressive cells from common marmoset ES cells by stepwise differentiation with DZNep.
Scientific reports - 28 Jul 2020
Tsuji Hyuma, Otsuka Ryo, Wada Haruka, Murata Tomoki, Sasaki Airi, Itoh Mizuho, Baghdadi Muhammad, Sasaki Erika, Seino Ken-Ichiro
Abstract excerpt
Recent progress in regenerative medicine has enabled the utilization of pluripotent stem cells (PSCs) as the resource of therapeutic cells/tissue. However, immune suppression is still needed when the donor-recipient combination is allogeneic. We have reported previously that mouse PSCs-derived immunosuppressive cells contribute to prolonged survival of grafts derived from the same mouse PSCs in allogeneic...
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