Article
New Immunosuppressive Cell Therapy to Prolong Survival of Induced Pluripotent Stem Cell-Derived Allografts.
Transplantation - 1 Nov 2015
Sasaki Hajime, Wada Haruka, Baghdadi Muhammad, Tsuji Hyuma, Otsuka Ryo, Morita Ken, Shinohara Nobuo, Seino Ken-Ichiro
Abstract excerpt
BACKGROUND: Induced pluripotent stem cell (iPSC) technology provides new opportunities in regenerative medicine to generate grafts from donors for transplantation. However, particularly when allogeneic iPSCs are used, immune suppression is required to avoid rejection of iPSC-derived grafts. In this study, we examine a concept that protection of iPSCs-derived allografts can be achieved when transplantation is...
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