Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variations of NKX2-5 in sporadic atrial septal defect and ventricular septal defect in Chinese Yunnan population.

Gene - 1 Jan 2016

Cao Yu, Wang Junqiang, Wei Chuanyu, Hou Zongliu, Li Yaxiong, Zou Honglin, Meng Mingyao, Wang Wenju, Jiang Lihong

Abstract excerpt

Congenital heart disease (CHD) is the most common birth abnormality, and more than 40% CHD subtypes are sporadic atrial septal defect (ASD) and ventricular septal defect (VSD). The etiology of ASD and VSD remains largely unknown. NKX2-5 gene is a highly conserved homeobox protein gene and expressed in the developing heart. Its mutations can cause sporadic ASD and VSD. This study aimed to investigate the genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to China

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Septal Defects, Atrial

Share to Homeobox Protein Nkx-2.5

Share to Homeodomain Proteins

Share to Introns

Share to Transcription Factors

Source

Identifiers

PMID: 26297999
DOI: 10.1016/j.gene.2015.08.033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variations of NKX2-5 in sporadic atrial septal defect and ventricular septal defect in Chinese Yunnan population.PMID 26297999Read ↗

NKX2-5 variants screening in patients with atrial septal defect in IndonesiaSemantic proximity Read ↗

Novel NKX2-5 mutations in patients with familial atrial septal defects.Semantic proximity Read ↗

Familial Atrial Septal Defect and Sudden Cardiac Death: Identification of a Novel NKX2-5 Mutation and a Review of the Literature.Semantic proximity Read ↗

Single nucleotide polymorphism of NKX2-5 gene with sporadic congenital heart disease in Chinese Bai population.Semantic proximity Read ↗

Prevalence and spectrum of NKX2.5 mutations in patients with congenital atrial septal defect and atrioventricular block.Semantic proximity Read ↗

A novel mutation in GATA4 gene associated with dominant inherited familial atrial septal defect.Semantic proximity Read ↗

[Mutation of NKX2-5 gene in patients with atrial septal defect].Semantic proximity Read ↗

[Novel NKX2-5 mutations identified in patients with congenital ventricular septal defects].Semantic proximity Read ↗

A Novel Splicing Mutation c.335-1 G > A in the Cardiac Transcription Factor NKX2-5 Leads to Familial Atrial Septal Defect Through miR-19 and PYK2.Semantic proximity Read ↗

Phenotypes with GATA4 or NKX2.5 mutations in familial atrial septal defect.Semantic proximity Read ↗

NKX2-5 mutations in an inbred consanguineous population: genetic and phenotypic diversity.Semantic proximity Read ↗

Mutational spectrum in the cardiac transcription factor gene NKX2.5 (CSX) associated with congenital heart disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.