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Article

Novel NKX2-5 mutations in patients with familial atrial septal defects.

Pediatric cardiology - 1 Feb 2011

Liu Xing-Yuan, Wang Juan, Yang Yi-Qing, Zhang Yang-Yang, Chen Xiao-Zhong, Zhang Wei, Wang Xiao-Zhou, Zheng Jing-Hao, Chen Yi-Han

Abstract excerpt

Atrial septal defect (ASD) is a common cardiovascular malformation and an important contributor to substantial morbidity and mortality. Increasing evidence demonstrates that mutated NKX2-5, a gene encoding a homeobox transcription factor crucial to cardiogenesis, is a significant genetic determin...

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Identifiers

PMID: 21188375
DOI: 10.1007/s00246-010-9859-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21188375-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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