Article
The axis inhibition protein 2 polymorphisms and non-syndromic orofacial clefts susceptibility in a Chinese Han population.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Aug 2014
Han Yue, Zhou Lian, Ma Lan, Li Dandan, Xu Min, Yuan Hua, Ma Junqing, Zhang Weibing, Jiang Hongbing, Wu Yunong, Wang Lin, Pan Yongchu
Abstract excerpt
BACKGROUND: The axis inhibition protein 2 (AXIN2) is an important regulator of β-catenin degradation in the Wnt pathway, which plays a key role in craniofacial morphogenesis. The goal of this study was to investigate the potential relationship between AXIN2 polymorphisms and the risks of non-syndromic orofacial clefts (NSOC) in a Chinese Han population. METHODS: Four polymorphisms of AXIN2 (rs2240307, rs11867417,...
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