Article
An A/C germline single-nucleotide polymorphism in the TNFAIP3 gene is associated with advanced disease stage and survival in only surgically treated esophageal cancer.
Journal of human genetics - 1 Dec 2014
Ghadban Tarik, Schmidt-Yang Magdalena, Smif Magdalena, Uzunoglu Faik G, Perez Daniel R, Tsui Tung Y, El Gammal Alexander T, Erbes Peter J, Zilbermints Veacheslav, Wellner Ulrich, Pantel Klaus, Izbicki Jakob R, Vashist Yogesh K
Abstract excerpt
Prognostication of disease relapse and survival is essential for cancer patients and genetic variations in cancer patients may serve as important indicators. A single-nucleotide polymorphism (SNP) mapping to the tumor necrosis factor, alpha-induced protein 3 (TNFAIP3) gene at position 138241110 displays three genotypes (AA, AC and CC). The aim of this study was to evaluate the potential prognostic value of the...
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