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Article

Genetic polymorphisms at TIMP3 are associated with survival of adenocarcinoma of the gastroesophageal junction.

PloS one - 1 Jan 2013

Bashash Morteza, Shah Amil, Hislop Greg, Treml Martin, Bretherick Karla, Janoo-Gilani Rozmin, Leach Stephen, Le Nhu, Bajdik Chris, Brooks-Wilson Angela

Abstract excerpt

The poor survival of adenocarcinomas of the gastroesophageal junction (GEJ) makes them clinically important. Discovery of host genetic factors that affect outcome may guide more individualized treatment. This study tests whether constitutional genetic variants in matrix metalloproteinases (MMP) and tissue inhibitors of metalloproteinases (TIMP) genes are associated with outcome of GEJ adenocarcinoma. Single...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 23527119
DOI: 10.1371/journal.pone.0059157
PMCID: PMC3602604

Genes

TIMP3
MMP2
MMP7
MMP9
TIMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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