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Article

Influence of genetic background and oxidative stress response on risk of mandibular osteoradionecrosis after radiotherapy of head and neck cancer.

Head & neck - 1 Mar 2016

Danielsson Daniel, Brehwens Karl, Halle Martin, Marczyk Michal, Sollazzo Alice, Polanska Joanna, Munck-Wikland Eva, Wojcik Andrzej, Haghdoost Siamak

Abstract excerpt

BACKGROUND: Osteoradionecrosis (ORN) of the mandible is a severe complication of head and neck radiotherapy (RT) treatment, where the impact of individual radiosensitivity has been a suggested explanation. METHODS: A cohort of patients with stage II/III ORN was compared to matched controls. Blood was collected and irradiated in vitro to study the capacity to handle radiation-induced oxidative stress. Patients...

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Source

Identifiers

PMID: 25352150
DOI: 10.1002/hed.23903

Genes

GSTP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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