Article
The association between hypoxia inducible factor-1alpha gene polymorphisms and increased susceptibility to oral cancer.
Oral oncology - 1 Dec 2009
Chen Mu-Kuan, Chiou Hui-Ling, Su Shih-Chi, Chung Tsung-Te, Tseng Hsien-Chun, Tsai Hsiu-Ting, Yang Shun-Fa
Abstract excerpt
The aim of this study was to estimate the relations between hypoxia inducible factor-1alpha (HIF-1alpha) gene polymorphisms, C1772T and G1790A, to the susceptibility and clinicopathological status of oral cancer. A total of 521 subjects, including 347 controls and 174 oral cancer patients, were recruited in this study and subjected to polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP)...
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