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Article

Single Nucleotide Polymorphisms in APE1, hOGG1, RAD51 Genes and their Association with Radiotherapy Induced Toxicity among Head and Neck Cancer Patients.

Asian Pacific journal of cancer prevention : APJCP - 1 Aug 2024

Gudur Anand K, Kale Shivani R, Gudur Rashmi A, Bhosale Suresh J, More Ashwini L, Datkhile Kailas D

Abstract excerpt

BACKGROUND: Radiotherapy (RT) is a crucial treatment for head and neck cancer however, it causes adverse reactions to the normal tissue and organs adjacent to target tumor. The present study was carried out to investigate possible association of single nucleotide polymorphism in DNA repair genes with toxicity effects of radiotherapy on normal tissue. METHODS: Three hundred and fifty head and neck cancer patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39205561
DOI: 10.31557/APJCP.2024.25.8.2645
PMCID: PMC11495438

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