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Article

Intake levels of dietary polyunsaturated fatty acids modify the association between the genetic variation in PCSK5 and HDL cholesterol.

Journal of medical genetics - 1 Dec 2014

Jang Han Byul, Hwang Joo-Yeon, Park Ji Eun, Oh Ji Hee, Ahn YounJhin, Kang Jae-Heon, Park Kyung-Hee, Han Bok-Ghee, Kim Bong Jo, Park Sang Ick, Lee Hye-Ja

Abstract excerpt

BACKGROUND: A low serum level of high-density lipoprotein cholesterol (HDL-C) is a risk factor for cardiovascular disease. Proprotein convertase subtilisin/kexin type 5 (PCSK5) modulates HDL-C metabolism through the inactivation of endothelial lipase activity. METHODS: Therefore, we analysed the effects of PCSK5 on HDL-C and investigated the association between genetic variation in PCSK5 and dietary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25351954
DOI: 10.1136/jmedgenet-2014-102670

Genes

PCSK5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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