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Article

What is the impact of PCSK9 rs505151 and rs11591147 polymorphisms on serum lipids level and cardiovascular risk: a meta-analysis.

Lipids in health and disease - 12 Jun 2017

Qiu Chengfeng, Zeng Pingyu, Li Xiaohui, Zhang Zhen, Pan Bingjie, Peng Zhou Y F, Li Yapei, Ma Yeshuo, Leng Yiping, Chen Ruifang

Abstract excerpt

BACKGROUND: PCSK9 rs505151 and rs11591147 polymorphisms are identified as gain- and loss-of-function mutations, respectively. The effects of these polymorphisms on serum lipid levels and cardiovascular risk remain to be elucidated. METHODS: In this meta-analysis, we explored the association of PCSK9 rs505151 and rs11591147 polymorphisms with serum lipid levels and cardiovascular risk by calculating the...

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Source

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Identifiers

PMID: 28606094
DOI: 10.1186/s12944-017-0506-6
PMCID: PMC5469167

Genes

PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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