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Article

Evaluation of PCSK9 levels and its genetic polymorphisms in women with polycystic ovary syndrome.

Gene - 20 Feb 2018

Xavier Luana B, Sóter Mirelle O, Sales Mariana F, Oliveira Daisy K, Reis Helton J, Candido Ana L, Reis Fernando M, Silva Ieda O, Gomes Karina B, Ferreira Cláudia N

Abstract excerpt

Dyslipidemia is one of the common metabolic disorders in Polycystic Ovary Syndrome (PCOS). Proprotein convertase subtilisin kexin type 9 (PCSK9) is a new component of lipid metabolism and correlated to the development of dyslipidemia and atherosclerosis. This protein acts by preventing the recycling of LDL receptors (LDL-r) back to the cell surface and thus generates higher levels of LDLc. The objective of this...

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Source

Identifiers

PMID: 29109005
DOI: 10.1016/j.gene.2017.11.006

Genes

PCSK9

Variants

rs562556
rs505151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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