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Article

Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels.

Circulation. Cardiovascular genetics - 1 Oct 2009

Iatan Iulia, Dastani Zari, Do Ron, Weissglas-Volkov Daphna, Ruel Isabelle, Lee Jenny C, Huertas-Vazquez Adriana, Taskinen Marja-Riitta, Prat Annik, Seidah Nabil G, Pajukanta Päivi, Engert James C, Genest Jacques

Abstract excerpt

BACKGROUND: A low level of plasma high-density lipoprotein cholesterol (HDL-C) is a risk factor for cardiovascular disease. HDL particles are modulated by a variety of lipases, including endothelial lipase, a phospholipase present on vascular endothelial cells. The proprotein convertase subtilisi...

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Identifiers

PMID: 20031622
DOI: 10.1161/CIRCGENETICS.109.877811
PMCID: PMC2901678

Genes

PCSK5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20031622-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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