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Article

Association Between Genetic Variants in the lncRNA-p53 Regulatory Network and Ischemic Stroke Prognosis.

Neurotoxicity research - 1 Aug 2021

Liu Xu, Wang Lu, Wang Qianwen, Zhao Jingjing, Chang Hongtao, Zhu Ruixia

Abstract excerpt

Long noncoding RNAs (lncRNAs) serve as regulators or effectors of the p53 regulatory pathway. The lncRNA-p53 regulatory network plays an important role in ischemia-induced apoptosis and may be important for post-stroke recovery. Eight genetic variants of p53-related lncRNAs were genotyped in 982 patients to explore the association of single nucleotide polymorphisms (SNPs) in the genes related to the p53...

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PMID: 33797738
DOI: 10.1007/s12640-021-00357-7

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