Article
MiR-SNPs as markers of toxicity and clinical outcome in Hodgkin lymphoma patients.
PloS one - 1 Jan 2013
Navarro Alfons, Muñoz Carmen, Gaya Anna, Díaz-Beyá Marina, Gel Bernat, Tejero Rut, Díaz Tania, Martinez Antonio, Monzó Mariano
Abstract excerpt
BACKGROUND: In recent years, microRNA (miRNA) pathways have emerged as a crucial system for the regulation of tumorogenesis. miR-SNPs are a novel class of single nucleotide polymorphisms that can affect miRNA pathways. DESIGN AND METHODS: We analyzed eight miR-SNPs by allelic discrimination in 141 patients with Hodgkin lymphoma and correlated the results with treatment-related toxicity, response, disease-free...
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