Methylenetetrahydrofolate reductase polymorphisms and susceptibility to acute lymphoblastic leukemia in a Chinese population: a meta-analysis.

doi:10.1159/000368104

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Article

Methylenetetrahydrofolate reductase polymorphisms and susceptibility to acute lymphoblastic leukemia in a Chinese population: a meta-analysis.

Oncology research and treatment - 1 Jan 2014

Xiao Yi, Deng Tao-Ran, Su Chang-Liang, Shang Zhen

Abstract excerpt

BACKGROUND: Although many epidemiologic studies have investigated the methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and their association with acute lymphoblastic leukemia (ALL), definitive conclusions cannot be drawn. To clarify the effects of MTHFR polymorphisms on the risk of ALL, a meta-analysis was performed in a Chinese population. MATERIALS AND METHODS: A computerized literature search was...

Topics

Adolescent
Age Distribution
Biomarkers, Tumor
Child
Child, Preschool
China
Female
Genetic Markers
Genetic Predisposition to Disease
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Methylenetetrahydrofolate Reductase (NADPH2)

Polymorphism, Single Nucleotide

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Prevalence

Risk Factors

Sex Distribution

Young Adult

Source

Open in PubMed

Identifiers

PMID: 25342508
DOI: 10.1159/000368104

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-25342508-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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