Article
The association between MTHFR gene C677T polymorphism and ALL risk based on a meta-analysis involving 17,469 subjects.
Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2017
Zhang Beibei, Zhang Weiming, Yan Liang, Wang Daogang
Abstract excerpt
BACKGROUND: The methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism is closely related to the acute lymphoblastic leukaemia (ALL) indicated by many previous epidemiologic studies. However, their conclusions were still conflicting. METHODS: Our aim is to evaluate their associations...
Topics
- Biomarkers, Tumor
- Case-Control Studies
- Genetic Predisposition to Disease
- Humans
- Methylenetetrahydrofolate Reductase (NADPH2)
- Polymorphism, Genetic
- Precursor Cell Lymphoblastic Leukemia-Lymphoma