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Article

Disentangling the roles of natural selection and genetic drift in shaping variation at MHC immunity genes.

Molecular ecology - 1 Nov 2011

Sutton Jolene T, Nakagawa Shinichi, Robertson Bruce C, Jamieson Ian G

Abstract excerpt

The major histocompatibility complex (MHC) forms an integral component of the vertebrate immune response and, due to strong selection pressures, is one of the most polymorphic regions of the entire genome. Despite over 15 years of research, empirical studies offer highly contradictory explanations of the relative roles of different evolutionary forces, selection and genetic drift, acting on MHC genes during...

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Identifiers

PMID: 21981032
DOI: 10.1111/j.1365-294X.2011.05292.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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