Article
Cyclooxygenase-2 genetic variants influence intratumoral infiltration of Foxp3-positive regulatory T cells in non-small cell lung cancer.
Oncology reports - 1 Jan 2015
Yukawa Takuro, Shimizu Katsuhiko, Maeda Ai, Yasuda Koichiro, Saisho Shinsuke, Okita Riki, Nakata Masao
Abstract excerpt
The immune microenvironment of primary tumors has been reported to be a prognostic factor. We previously reported that the tumor-infiltrating regulatory T cell (Treg) count was positively correlated with the intratumoral cyclooxygenase-2 (COX-2) expression level and was associated with a poor sur...
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