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Article

FOXP3 and TLR4 protein expression are correlated in non-small cell lung cancer: implications for tumor progression and escape.

Acta histochemica - 1 Mar 2013

Fu Hai-ying, Li Chun, Yang Wei, Gai Xiao-dong, Jia Ting, Lei Yan-ming, Li Yi

Abstract excerpt

NSCLC (non-small cell lung cancer) is the most common type of lung cancer and usually has poor prognosis. FOXP3 in regulatory T cells (Tregs) and toll-like receptor 4 (TLR4) on some tumor cells are known to be important for tumor escape and clinical tumor formation. Since FOXP3 was found recently in some tumor cells, we speculated if lung tumor cells express FOXP3 and then mimic Tregs to promote tumor escape. As...

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Source

Identifiers

PMID: 22749378
DOI: 10.1016/j.acthis.2012.06.002

Genes

FOXP3
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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