Article
Cox-2 and IL-10 polymorphisms and association with squamous cell carcinoma of the head and neck in a Korean sample.
Journal of Korean medical science - 1 Jul 2010
Jeong Seung Won, Tae Kyung, Lee Seung Hwan, Kim Kyung Rae, Park Chul Won, Park Byung Lae, Shin Hyoung Doo
Abstract excerpt
Cyclooxygenase-2 (COX-2) is involved in inflammation and carcinogenesis. Interleukin-10 (IL-10) is also regarded as anti-inflammatory factors with the multi-functional ability to positively and negatively influence functional immunity and tumor development. Genetic polymorphisms of COX-2 and IL-10 might contribute to the development of squamous cell carcinoma of the head and neck (SCCHN). The purpose of this...
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