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Article

Cyclooxygenase-2 genetic variants are associated with survival in unresectable locally advanced non-small cell lung cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2010

Bi Nan, Yang Ming, Zhang Li, Chen Xiabin, Ji Wei, Ou Guangfei, Lin Dongxin, Wang Luhua

Abstract excerpt

PURPOSE: Cyclooxygenase-2 (COX-2) plays important roles in the modulation of apoptosis, angiogenesis, immune response, and tumor invasion. Elevated COX-2 expression has been reported to be correlated with reduced survival after radiotherapy. This study examined whether genetic variations in the COX-2 gene are associated with different survival in inoperable locally advanced non-small cell lung cancer (NSCLC)...

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Source

Identifiers

PMID: 20332326
DOI: 10.1158/1078-0432.CCR-09-2793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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