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Article

Association between endometriosis and the interleukin 1A (IL1A) locus.

Human reproduction (Oxford, England) - 1 Jan 2015

Sapkota Yadav, Low Siew-Kee, Attia John, Gordon Scott D, Henders Anjali K, Holliday Elizabeth G, MacGregor Stuart, Martin Nicholas G, McEvoy Mark, Morris Andrew P, Takahashi Atsushi, Scott Rodney J, Kubo Michiaki, Zondervan Krina T, Montgomery Grant W, Nyholt Dale R

Abstract excerpt

STUDY QUESTION: Are single-nucleotide polymorphisms (SNPs) at the interleukin 1A (IL1A) gene locus associated with endometriosis risk? SUMMARY ANSWER: We found evidence for strong association between IL1A SNPs and endometriosis risk. WHAT IS KNOWN ALREADY: Genetic factors contribute substantially to the complex aetiology of endometriosis and the disease has an estimated heritability of ∼51%. We, and others, have...

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Source

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Identifiers

PMID: 25336714
DOI: 10.1093/humrep/deu267
PMCID: PMC4262465

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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