Article

M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy with Comorbid Traits

2024-11-22

Abstract excerpt

Endometriosis is a common gynecologic condition that causes chronic life-altering symptoms including pain, infertility, and elevated cancer risk. There is an urgent need for new non-hormonal targeted therapeutics to treat endometriosis, but until very recently, the cellular and molecular signatures of endometriotic lesions were undefined, severely hindering the development of clinical advances. Integrating inherit...

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Literature Corpus work: fde9ad28-262f-5243-a3e5-a3bc10cdb086
DOI: 10.1101/2024.11.21.624726

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