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Article

Polymorphisms of TNF-alpha (- 308), IL-1beta (+ 3954) and IL1-Ra (VNTR) are associated to severe stage of endometriosis in Mexican women: a case control study.

BMC women's health - 26 Aug 2022

Mier-Cabrera Jennifer, Cruz-Orozco Oliver, de la Jara-Díaz Julio, Galicia-Castillo Oscar, Buenrostro-Jáuregui Mario, Parra-Carriedo Alicia, Hernández-Guerrero César

Abstract excerpt

BACKGROUND: Endometriosis is an estrogen-dependent and chronic inflammatory disease affecting up to 10% of women. It is the result of a combined interaction of genetic, epigenetic, environmental, lifestyle, reproductive and local inflammatory factors. In this study, we investigated whether single nucleotide polymorphisms (SNPs) mapping to TNF-alpha (TNF, rs1800629) and IL-1beta (IL1B, rs1143634) and variable...

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Identifiers

PMID: 36028805
DOI: 10.1186/s12905-022-01941-5
PMCID: PMC9413921

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