Article
Independent Replication and Meta-Analysis for Endometriosis Risk Loci.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Oct 2015
Sapkota Yadav, Fassbender Amelie, Bowdler Lisa, Fung Jenny N, Peterse Daniëlle, O Dorien, Montgomery Grant W, Nyholt Dale R, D'Hooghe Thomas M
Abstract excerpt
Endometriosis is a complex disease that affects 6-10% of women in their reproductive years and 20-50% of women with infertility. Genome-wide and candidate-gene association studies for endometriosis have identified 10 independent risk loci, and of these, nine (rs7521902, rs13394619, rs4141819, rs6542095, rs1519761, , , , and ) are polymorphic in European populations. Here we...