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Genetic Variation at Chromosome 2q13 and Its Potential Influence on Endometriosis Susceptibility Through Effects on the IL-1 Family.

Reproductive sciences (Thousand Oaks, Calif.) - 1 Sept 2018

Gajbhiye Rahul, McKinnon Brett, Mortlock Sally, Mueller Michael, Montgomery Grant

Abstract excerpt

Endometriosis is characterized by the growth of epithelial and stromal cells outside the uterine cavity. It has a complex etiology and affects ∼10% of reproductive age women. It is accompanied by a chronic inflammatory response with substantial evidence to indicate genetic susceptibility. The causal genes and their pathways leading to endometriosis, however, are still unknown. Recently, genomewide association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29669463
DOI: 10.1177/1933719118768688

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