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Article

Methylation profiling of ductal carcinoma in situ and its relationship to histopathological features.

Breast cancer research : BCR - 21 Oct 2014

Pang Jia-Min B, Deb Siddhartha, Takano Elena A, Byrne David J, Jene Nicholas, Boulghourjian Alice, Holliday Anne, Millar Ewan, Lee C Soon, O'Toole Sandra A, Dobrovic Alexander, Fox Stephen B

Abstract excerpt

INTRODUCTION: DNA methylation is a well-studied biomarker in invasive breast cancer, but its role in ductal carcinoma in situ (DCIS) is less well characterized. The aims of this study are to assess the methylation profile in DCIS for a panel of well-characterized genes that are frequently methylated in breast cancer, to investigate the relationship of methylation with pathological features, and to perform a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Intraductal, Noninfiltrating

Share to CpG Islands

Share to DNA Methylation

Share to Epigenesis, Genetic

Share to Gene Expression Regulation, Neoplastic

Share to Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 25331261
DOI: 10.1186/s13058-014-0423-9
PMCID: PMC4303108

Genes

CDH13
APC
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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