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Article

DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer

24 Jul 2015

Abstract excerpt

BACKGROUND: Ductal carcinoma in situ (DCIS) is a heterogeneous, pre-invasive lesion associated with an increased risk for future invasive ductal carcinoma. However, accurate risk stratification for development of invasive disease and appropriate treatment decisions remain clinical challenges. DNA methylation alterations are early events in the progression of cancer and represent emerging molecular markers that...

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PMID: 26213588
DOI: 10.1186/s13148-015-0094-0

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