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Article

Hypermethylated genes as biomarkers of cancer in women with pathologic nipple discharge.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2009

Fackler Mary Jo, Rivers Aeisha, Teo Wei Wen, Mangat Amrit, Taylor Evangeline, Zhang Zhe, Goodman Steve, Argani Pedram, Nayar Ritu, Susnik Barbara, Sukumar Saraswati, Khan Seema A

Abstract excerpt

PURPOSE: In a pilot study of women with pathologic nipple discharge (PND) undergoing ductoscopy, we tested quantitative assessment of gene promoter hypermethylation using quantitative multiplex methylation-specific PCR (QM-MSP) to enhance detection of duct carcinoma in situ (DCIS). EXPERIMENTAL DESIGN: Women with PND underwent ductoscopy; ducts with significant lesions were surgically resected (36 ducts in 33...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19470737
DOI: 10.1158/1078-0432.CCR-08-1981

Genes

TWIST1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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