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Article

KDM5 interacts with Foxo to modulate cellular levels of oxidative stress.

PLoS genetics - 1 Oct 2014

Liu Xingyin, Greer Christina, Secombe Julie

Abstract excerpt

Increased cellular levels of oxidative stress are implicated in a large number of human diseases. Here we describe the transcription co-factor KDM5 (also known as Lid) as a new critical regulator of cellular redox state. Moreover, this occurs through a novel KDM5 activity whereby it alters the ab...

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Identifiers

PMID: 25329053
DOI: 10.1371/journal.pgen.1004676
PMCID: PMC4199495

Genes

HDAC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25329053-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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