Article
Estimation of epistatic variance components and heritability in founder populations and crosses.
Genetics - 1 Dec 2014
Young Alexander I, Durbin Richard
Abstract excerpt
Genetic association studies have explained only a small proportion of the estimated heritability of complex traits, leaving the remaining heritability "missing." Genetic interactions have been proposed as an explanation for this, because they lead to overestimates of the heritability and are hard to detect. Whether this explanation is true depends on the proportion of variance attributable to genetic...
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