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Article

Association of rs172378 C1q gene cluster polymorphism with lupus nephritis in Bulgarian patients.

Lupus - 1 Mar 2015

Radanova M, Vasilev V, Dimitrov T, Deliyska B, Ikonomov V, Ivanova D

Abstract excerpt

INTRODUCTION: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that can affect substantially any organ in the body. One of its most severe manifestations is lupus nephritis. Hereditary C1q deficiency is strongly related to SLE but there are very few and inconsistent studies exploring the single nucleotide polymorphisms (SNPs) of the C1q gene cluster in relation to the pathogenesis of SLE. In...

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PMID: 25326229
DOI: 10.1177/0961203314555173

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