Article
Association of C1q gene cluster variants with rheumatoid arthritis: a pilot study.
Rheumatology international - 1 Jun 2022
Kosturkova Mariya Blagoeva, Mihaylova Galya Mihaylova, Shivacheva Tanya Kirilova, Radanova Maria Atanasova
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) in C1q gene cluster were previously linked to autoimmunity and SLE, but data are scarce for their association with RA. In the present study, we evaluated associations of five SNPs (rs665691, rs682658, rs172378, rs292001 and rs294179) in the C1q genetic region with RA and some of its clinical and immunologic characteristics. Fifty-eight RA patients and 67 age- and...